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Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity

Heat-shock response is an adaptive response to proteotoxic stresses including heat shock, and is regulated by heat-shock factor 1 (HSF1) in mammals. Proteotoxic stresses challenge all subcellular compartments including the mitochondria. Therefore, there must be close connections between mitochondria...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Tan, Ke, Fujimoto, Mitsuaki, Takii, Ryosuke, Takaki, Eiichi, Hayashida, Naoki, Nakai, Akira
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558571/
https://ncbi.nlm.nih.gov/pubmed/25762445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7580
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