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Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT
Heat shock transcription factor 1 (HSF1) is an important regulator of protein homeostasis (proteostasis) by controlling the expression of major heat shock proteins (Hsps) that facilitate protein folding. However, it is unclear whether other proteostasis pathways are mediated by HSF1. Here, we identi...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2964172/ https://ncbi.nlm.nih.gov/pubmed/20834230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.225 |
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