α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway

α-Solanine is a glycoalkaloid found in species of the nightshade family including potato. It was primarily reported to have toxic effects in humans. However, there is a growing body of literature demonstrating in vitro and in vivo anticancer activity of α-solanine. Most of these studies have shown a...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hasanain, M, Bhattacharjee, A, Pandey, P, Ashraf, R, Singh, N, Sharma, S, Vishwakarma, A L, Datta, D, Mitra, K, Sarkar, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558510/
https://ncbi.nlm.nih.gov/pubmed/26313911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.219
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