Silencing NFBD1/MDC1 enhances the radiosensitivity of human nasopharyngeal cancer CNE1 cells and results in tumor growth inhibition

NFBD1 functions in cell cycle checkpoint activation and DNA repair following ionizing radiation (IR). In this study, we defined the NFBD1 as a tractable molecular target to radiosensitize nasopharyngeal carcinoma (NPC) cells. Silencing NFBD1 using lentivirus-mediated shRNA-sensitized NPC cells to ra...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Z, Zeng, Q, Chen, T, Liao, K, Bu, Y, Hong, S, Hu, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558506/
https://ncbi.nlm.nih.gov/pubmed/26247734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.214
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