A new small molecule inhibitor of soluble guanylate cyclase

Soluble guanylate cyclase (sGC) is a haem containing enzyme that regulates cardiovascular homeostasis and multiple mechanisms in the central and peripheral nervous system. Commonly used inhibitors of sGC activity act through oxidation of the haem moiety, however they also bind haemoglobin and this l...

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Detaylı Bibliyografya
Yayımlandı:Bioorg Med Chem
Asıl Yazarlar: Mota, Filipa, Gane, Paul, Hampden-Smith, Kathryn, Allerston, Charles K., Garthwaite, John, Selwood, David L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Science 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558462/
https://ncbi.nlm.nih.gov/pubmed/26264842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.07.074
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