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An allosteric interaction links USP7 to deubiquitination and chromatin targeting of UHRF1
The protein stability and chromatin functions of UHRF1 (Ubiquitin-like, containing PHD and RING Finger domains, 1) are regulated in a cell cycle-dependent manner. We report a structural characterization of the complex between UHRF1 and the deubiquitinase USP7. The first two UBL domains of USP7 bind...
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| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558366/ https://ncbi.nlm.nih.gov/pubmed/26299963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.046 |
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