Selective killing of breast cancer cells expressing activated CD44 using CD44 ligand-coated nanoparticles in vitro and in vivo

The cell surface glycoprotein CD44 is expressed in cancer cells and has been used as a therapeutic target in preclinical studies. However, the ubiquitous expression of CD44 in numerous cell types, including hematopoietic cells, has hindered its application in targeted therapy. Here, we demonstrated...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Yang, Cuixia, He, Yiqing, Zhang, Huizhen, Liu, Yiwen, Wang, Wenjuan, Du, Yan, Gao, Feng
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558151/
https://ncbi.nlm.nih.gov/pubmed/25909172
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