Irreversible dual inhibitory mode: the novel Btk inhibitor PLS-123 demonstrates promising anti-tumor activity in human B-cell lymphoma

The B-cell receptor (BCR) signaling pathway has gained significant attention as a therapeutic target in B-cell malignancies. Recently, several drugs that target the BCR signaling pathway, especially the Btk inhibitor ibrutinib, have demonstrated notable therapeutic effects in relapsed/refractory pat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ding, Ning, Li, Xitao, Shi, Yunfei, Ping, Lingyan, Wu, Lina, Fu, Kai, Feng, Lixia, Zheng, Xiaohui, Song, Yuqin, Pan, Zhengying, Zhu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558140/
https://ncbi.nlm.nih.gov/pubmed/25944695
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