PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression

To overcome cancer cells resistance to pharmacological therapy, the development of new therapeutic approaches becomes urgent. For this purpose, the use of poly(ADP-ribose) polymerase (PARP) inhibitors in combination with other cytotoxic agents could represent an efficacious strategy. Poly(ADP-ribosy...

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Udgivet i:Oncotarget
Main Authors: Mariano, Germano, Ricciardi, Maria Rosaria, Trisciuoglio, Daniela, Zampieri, Michele, Ciccarone, Fabio, Guastafierro, Tiziana, Calabrese, Roberta, Valentini, Elisabetta, Tafuri, Agostino, Del Bufalo, Donatella, Caiafa, Paola, Reale, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558132/
https://ncbi.nlm.nih.gov/pubmed/25938539
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