CCCTC-binding Factor Activates PARP-1 Affecting DNA Methylation Machinery

Our previous data have shown that in L929 mouse fibroblasts the control of methylation pattern depends in part on poly(ADP-ribosyl)ation and that ADP-ribose polymers (PARs), both present on poly(ADP-ribosyl)ated PARP-1 and/or protein-free, have an inhibitory effect on Dnmt1 activity. Here we show th...

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Autors principals: Guastafierro, Tiziana, Cecchinelli, Barbara, Zampieri, Michele, Reale, Anna, Riggio, Giuseppe, Sthandier, Olga, Zupi, Gabriella, Calabrese, Lilia, Caiafa, Paola
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Transcription, Chromatin, and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494936/
https://ncbi.nlm.nih.gov/pubmed/18539602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801170200
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