RRAD inhibits the Warburg effect through negative regulation of the NF-κB signaling

Cancer cells preferentially use aerobic glycolysis to meet their increased energetic and biosynthetic demands, a phenomenon known as the Warburg effect. Its underlying mechanism is not fully understood. RRAD, a small GTPase, is a potential tumor suppressor in lung cancer. RRAD expression is frequent...

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Publicat a:Oncotarget
Autors principals: Liu, Juan, Zhang, Cen, Wu, Rui, Lin, Meihua, Liang, Yingjian, Liu, Jia, Wang, Xiaolong, Yang, Bo, Feng, Zhaohui
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558130/
https://ncbi.nlm.nih.gov/pubmed/25893381
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