MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling

Tumor suppressor p53 plays a central role in tumor suppression. To ensure its proper function, the levels and activity of p53 are under a tight regulation in cells. MicroRNAs are short non-coding RNAs that play an important role in regulation of gene expression. Recently, microRNA-339-5p has been re...

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Vydáno v:Oncotarget
Hlavní autoři: Zhang, Cen, Liu, Juan, Wang, Xiaolong, Wu, Rui, Lin, Meihua, Laddha, Saurabh V., Yang, Qifeng, Chan, Chang S., Feng, Zhaohui
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253422/
https://ncbi.nlm.nih.gov/pubmed/25193859
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