Llwytho...

The regulation of the p53/MDM2 feedback loop by microRNAs

Tumor suppressor p53 and its signaling pathway play a central role in tumor prevention. The E3 ubiquitin ligase MDM2, which is a direct p53 transcriptional target and also the most critical negative regulator of p53, forms an autoregulatory negative feedback loop with p53 in the cell to tightly regu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RNA Dis
Prif Awduron: Zhang, Cen, Liu, Juan, Wang, Xiaolong, Feng, Zhaohui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435570/
https://ncbi.nlm.nih.gov/pubmed/25995995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/rd.502
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