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Chemistry of Renieramycins. Part 14: Total Synthesis of Renieramycin I and Practical Synthesis of Cribrostatin 4 (Renieramycin H)

The first total synthesis of (±)-renieramycin I, which was isolated from the Indian bright blue sponge Haliclona cribricutis, is described. The key step is the selenium oxide oxidation of pentacyclic bis-p-quinone derivative (3) stereo- and regioselectively. We also report a large-scale synthesis of...

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Vydáno v:Mar Drugs
Hlavní autoři: Yokoya, Masashi, Kobayashi, Keiichiro, Sato, Mitsuhiro, Saito, Naoki
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557007/
https://ncbi.nlm.nih.gov/pubmed/26287215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13084915
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