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Total Synthesis of Cribrostatin 6

The total synthesis of antimicrobial and antineoplastic cribrostatin 6 was accomplished in only four steps in the longest linear sequence and five total steps from commercially available starting materials. The key step employed a tandem 4-π electrocyclic ring opening, radical cyclization, and homol...

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Detalhes bibliográficos
Main Authors: Knueppel, Daniel, Martin, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790822/
https://ncbi.nlm.nih.gov/pubmed/19235818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200806269
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