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The clinical potential of inotuzumab ozogamicin in relapsed and refractory acute lymphocytic leukemia

Antibody–drug conjugates (ADCs) are likely to make a significant contribution in the treatment of acute lymphoblastic leukemia (ALL) by combining the cytotoxicity of chemotherapy with the specificity of monoclonal antibodies. CD22, an endocytic receptor expressed by the majority of B cells, is an ex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Ther Adv Hematol
Hauptverfasser: Yilmaz, Musa, Richard, Samantha, Jabbour, Elias
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556970/
https://ncbi.nlm.nih.gov/pubmed/26425338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715596715
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