Results of Inotuzumab Ozogamicin, a CD22 Monoclonal Antibody in Refractory and Relapsed Acute Lymphocytic Leukemia

BACKGROUND: CD22 expression occurs in > 90% of patients with ALL. Inotuzumab ozogamicin, a CD22 monoclonal antibody bound to calicheamicin, is active in ALL. METHODS: Patients with refractory-relapsed ALL were treated with inotuzumab. The first 49 patients received single-dose inotuzumab 1.3-1.8...

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Main Authors: Kantarjian, Hagop, Thomas, Deborah, Jorgensen, Jeffrey, Kebriaei, Partow, Jabbour, Elias, Rytting, Michael, York, Sergernne, Ravandi, Farhad, Garris, Rebecca, Kwari, Monica, Faderl, Stefan, Cortes, Jorge, Champlin, Richard, O'Brien, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720844/
https://ncbi.nlm.nih.gov/pubmed/23633004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28136
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