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Role of inotuzumab ozogamicin in the treatment of relapsed/refractory acute lymphoblastic leukemia

Inotuzumab ozogamicin is a humanized anti-CD22 monoclonal antibody bound to a toxic natural calicheamicin, which is under investigation for the treatment of relapsed/refractory acute lymphoblastic leukemia. CD22 is commonly expressed in 90–100% of malignant mature B-lymphocyte lineage. The first Pha...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: George, Binsah, Kantarjian, Hagop, Jabbour, Elias, Jain, Nitin
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618942/
https://ncbi.nlm.nih.gov/pubmed/26780449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.15.108
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