BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins

The potent trypanolytic properties of human apolipoprotein L1 (APOL1) can be neutralized by the trypanosome variant surface antigen gene product known as serum resistance-associated protein. However, two common APOL1 haplotypes present uniquely in individuals of West African ancestry each encode APO...

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Udgivet i:Am J Physiol Cell Physiol
Main Authors: Heneghan, J. F., Vandorpe, D. H., Shmukler, B. E., Giovinazzo, J. A., Raper, J., Friedman, D. J., Pollak, M. R., Alper, S. L.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556898/
https://ncbi.nlm.nih.gov/pubmed/26108665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00142.2015
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