BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells

Familial history remains the strongest risk factor for developing ovarian cancer (OC) and is associated with germline BRCA1 mutations, such as the 185delAG founder mutation. We sought to determine whether normal human ovarian surface epithelial (OSE) cells expressing the BRCA1 185delAG mutant, BRAT,...

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Publicat a:Biomed Res Int
Autors principals: Woolery, Kamisha T., Mohamed, Mai, Linger, Rebecca J., Dobrinski, Kimberly P., Roman, Jesse, Kruk, Patricia A.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556869/
https://ncbi.nlm.nih.gov/pubmed/26357657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/652017
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