BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells

Familial history remains the strongest risk factor for developing ovarian cancer (OC) and is associated with germline BRCA1 mutations, such as the 185delAG founder mutation. We sought to determine whether normal human ovarian surface epithelial (OSE) cells expressing the BRCA1 185delAG mutant, BRAT,...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Woolery, Kamisha T., Mohamed, Mai, Linger, Rebecca J., Dobrinski, Kimberly P., Roman, Jesse, Kruk, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556869/
https://ncbi.nlm.nih.gov/pubmed/26357657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/652017
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