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Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells

ATP is essential for cellular function and is usually produced through oxidative phosphorylation. However, mitochondrial dysfunction is now being recognized as an important contributing factor in the development cardiovascular diseases, such as pulmonary hypertension (PH). In PH there is a metabolic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Redox Biol
Prif Awduron: Rafikov, Ruslan, Sun, Xutong, Rafikova, Olga, Louise Meadows, Mary, Desai, Ankit A., Khalpey, Zain, Yuan, Jason X.-J., Fineman, Jeffrey R., Black, Stephen M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556771/
https://ncbi.nlm.nih.gov/pubmed/26298201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.07.016
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