Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer

Vaccinia virus A33 is an extracellular enveloped virus (EEV)-specific type II membrane glycoprotein that is essential for efficient EEV formation and long-range viral spread within the host. A33 is a target for neutralizing antibody responses against EEV. In this study, we produced seven murine anti...

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Publicat a:PLoS Pathog
Autors principals: Matho, Michael H., Schlossman, Andrew, Meng, Xiangzhi, Benhnia, Mohammed Rafii-El-Idrissi, Kaever, Thomas, Buller, Mark, Doronin, Konstantin, Parker, Scott, Peters, Bjoern, Crotty, Shane, Xiang, Yan, Zajonc, Dirk M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556652/
https://ncbi.nlm.nih.gov/pubmed/26325270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005148
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