Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

Although mammalian long non-coding (lnc)RNAs are best known for modulating transcription, their post-transcriptional influence on mRNA splicing, stability and translation is emerging. Here we report a post-translational function for the lncRNA HOTAIR as an inducer of ubiquitin-mediated proteolysis....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yoon, Je-Hyun, Abdelmohsen, Kotb, Kim, Jiyoung, Yang, Xiaoling, Martindale, Jennifer L., Tominaga-Yamanaka, Kumiko, White, Elizabeth J., Orjalo, Arturo V., Rinn, John L., Kreft, Stefan G., Wilson, Gerald M., Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556280/
https://ncbi.nlm.nih.gov/pubmed/24326307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3939
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