טוען...
APC is required for muscle stem cell proliferation and skeletal muscle tissue repair
The tumor suppressor adenomatous polyposis coli (APC) is a crucial regulator of many stem cell types. In constantly cycling stem cells of fast turnover tissues, APC loss results in the constitutive activation of a Wnt target gene program that massively increases proliferation and leads to malignant...
שמור ב:
| הוצא לאור ב: | J Cell Biol |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4555822/ https://ncbi.nlm.nih.gov/pubmed/26304725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501053 |
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