APC is required for muscle stem cell proliferation and skeletal muscle tissue repair

The tumor suppressor adenomatous polyposis coli (APC) is a crucial regulator of many stem cell types. In constantly cycling stem cells of fast turnover tissues, APC loss results in the constitutive activation of a Wnt target gene program that massively increases proliferation and leads to malignant...

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Vydáno v:J Cell Biol
Hlavní autoři: Parisi, Alice, Lacour, Floriane, Giordani, Lorenzo, Colnot, Sabine, Maire, Pascal, Le Grand, Fabien
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555822/
https://ncbi.nlm.nih.gov/pubmed/26304725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501053
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