APC is required for muscle stem cell proliferation and skeletal muscle tissue repair

The tumor suppressor adenomatous polyposis coli (APC) is a crucial regulator of many stem cell types. In constantly cycling stem cells of fast turnover tissues, APC loss results in the constitutive activation of a Wnt target gene program that massively increases proliferation and leads to malignant...

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Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Parisi, Alice, Lacour, Floriane, Giordani, Lorenzo, Colnot, Sabine, Maire, Pascal, Le Grand, Fabien
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2015
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555822/
https://ncbi.nlm.nih.gov/pubmed/26304725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501053
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