Anti-angiogenic and anti-proliferative effects of inhibition of HIF-1α by p-HIF-1α RNAi in colorectal cancer

The aim of this study was to construct an RNA-interference plasmid (p-HIF-1α RNAi) targeting the human HIF-1α gene and assess its effects on HIF-1α expression and its anti-tumour functions in vitro. p-HIF-1α RNAi was constructed and confirmed by polymerase chain reaction (PCR) and DNA sequencing. Re...

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Detalles Bibliográficos
Publicado en:Int J Clin Exp Pathol
Autores principales: Qiu, Yan-Yan, Hu, Song-Jiao, Bao, Yi-Jie, Liang, Bo, Yan, Cui-Na, Shi, Xiao-Jing, Yu, Hui, Zou, Yu, Tang, Li-Rui, Tang, Qing-Feng, Feng, Wen, Yin, Pei-Hao
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555684/
https://ncbi.nlm.nih.gov/pubmed/26339356
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