Phenotypic Assays to Identify Agents That Induce Reactive Gliosis: A Counter-Screen to Prioritize Compounds for Preclinical Animal Studies

Astrocyte phenotypes change in a process called reactive gliosis after traumatic central nervous system (CNS) injury. Astrogliosis is characterized by expansion of the glial fibrillary acidic protein (GFAP) cytoskeleton, adoption of stellate morphologies, and differential expression of some extracel...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Assay Drug Dev Technol
Main Authors: Beckerman, Samuel R., Jimenez, Joaquin E., Shi, Yan, Al-Ali, Hassan, Bixby, John L., Lemmon, Vance P.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555645/
https://ncbi.nlm.nih.gov/pubmed/26230074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.654
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki