Phenotypic Assays to Identify Agents That Induce Reactive Gliosis: A Counter-Screen to Prioritize Compounds for Preclinical Animal Studies

Astrocyte phenotypes change in a process called reactive gliosis after traumatic central nervous system (CNS) injury. Astrogliosis is characterized by expansion of the glial fibrillary acidic protein (GFAP) cytoskeleton, adoption of stellate morphologies, and differential expression of some extracel...

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Xehetasun bibliografikoak
Argitaratua izan da:Assay Drug Dev Technol
Egile Nagusiak: Beckerman, Samuel R., Jimenez, Joaquin E., Shi, Yan, Al-Ali, Hassan, Bixby, John L., Lemmon, Vance P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2015
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555645/
https://ncbi.nlm.nih.gov/pubmed/26230074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.654
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