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Identifying problematic drugs based on the characteristics of their targets

Identifying promising compounds during the early stages of drug development is a major challenge for both academia and the pharmaceutical industry. The difficulties are even more pronounced when we consider multi-target pharmacology, where the compounds often target more than one protein, or multipl...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Lopes, Tiago J. S., Shoemaker, Jason E., Matsuoka, Yukiko, Kawaoka, Yoshihiro, Kitano, Hiroaki
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555035/
https://ncbi.nlm.nih.gov/pubmed/26388775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00186
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