Network-Guided Discovery of Influenza Virus Replication Host Factors

The positions of host factors required for viral replication within a human protein-protein interaction (PPI) network can be exploited to identify drug targets that are robust to drug-mediated selective pressure. Host factors can physically interact with viral proteins, be a component of virus-regul...

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Veröffentlicht in:mBio
Hauptverfasser: Ackerman, Emily E., Kawakami, Eiryo, Katoh, Manami, Watanabe, Tokiko, Watanabe, Shinji, Tomita, Yuriko, Lopes, Tiago J., Matsuoka, Yukiko, Kitano, Hiroaki, Shoemaker, Jason E., Kawaoka, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299219/
https://ncbi.nlm.nih.gov/pubmed/30563907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02002-18
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