A background Ca(2+) entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling

AIMS: Pathological cardiac hypertrophy is a major predictor for the development of cardiac diseases. It is associated with chronic neurohumoral stimulation and with altered cardiac Ca(2+) signalling in cardiomyocytes. TRPC proteins form agonist-induced cation channels, but their functional role for...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Camacho Londoño, Juan E., Tian, Qinghai, Hammer, Karin, Schröder, Laura, Camacho Londoño, Julia, Reil, Jan C., He, Tao, Oberhofer, Martin, Mannebach, Stefanie, Mathar, Ilka, Philipp, Stephan E., Tabellion, Wiebke, Schweda, Frank, Dietrich, Alexander, Kaestner, Lars, Laufs, Ulrich, Birnbaumer, Lutz, Flockerzi, Veit, Freichel, Marc, Lipp, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554959/
https://ncbi.nlm.nih.gov/pubmed/26069213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv250
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