The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone

AIMS: Signalling via cGMP-dependent protein kinase I (cGKI) is the major pathway in vascular smooth muscle (SM), by which endothelial NO regulates vascular tone. Recent evidence suggests that canonical transient receptor potential (Trpc) channels are targets of cGKI in SM and mediate the relaxant ef...

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Detalhes bibliográficos
Main Authors: Loga, Florian, Domes, Katrin, Freichel, Marc, Flockerzi, Veit, Dietrich, Alexander, Birnbaumer, Lutz, Hofmann, Franz, Wegener, Jörg W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797626/
https://ncbi.nlm.nih.gov/pubmed/23832809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt176
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