The role of cGMP/cGKI signalling and Trpc channels in regulation of vascular tone

AIMS: Signalling via cGMP-dependent protein kinase I (cGKI) is the major pathway in vascular smooth muscle (SM), by which endothelial NO regulates vascular tone. Recent evidence suggests that canonical transient receptor potential (Trpc) channels are targets of cGKI in SM and mediate the relaxant ef...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Loga, Florian, Domes, Katrin, Freichel, Marc, Flockerzi, Veit, Dietrich, Alexander, Birnbaumer, Lutz, Hofmann, Franz, Wegener, Jörg W.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797626/
https://ncbi.nlm.nih.gov/pubmed/23832809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt176
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