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Development of a Full-Thickness Human Skin Equivalent In Vitro Model Derived from TERT-Immortalized Keratinocytes and Fibroblasts

Currently, human skin equivalents (HSEs) used for in vitro assays (e.g., for wound healing) make use of primary human skin cells. Limitations of primary keratinocytes and fibroblasts include availability of donor skin and donor variation. The use of physiologically relevant cell lines could solve th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Tissue Eng Part A
Hauptverfasser: Reijnders, Christianne M.A., van Lier, Amanda, Roffel, Sanne, Kramer, Duco, Scheper, Rik J., Gibbs, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554934/
https://ncbi.nlm.nih.gov/pubmed/26135533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2015.0139
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