The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase.

In Saccharomyces cerevisiae, mutations in FKS1 confer hypersensitivity to the immunosuppressants FK506 and cyclosporin A, while mutations in ETG1 confer resistance to the cell-wall-active echinocandins (inhibitors of 1,3-beta-D-glucan synthase) and, in some cases, concomitant hypersensitivity to the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Douglas, C M, Foor, F, Marrinan, J A, Morin, N, Nielsen, J B, Dahl, A M, Mazur, P, Baginsky, W, Li, W, el-Sherbeini, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45549/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7528927/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12907
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