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The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase.

In Saccharomyces cerevisiae, mutations in FKS1 confer hypersensitivity to the immunosuppressants FK506 and cyclosporin A, while mutations in ETG1 confer resistance to the cell-wall-active echinocandins (inhibitors of 1,3-beta-D-glucan synthase) and, in some cases, concomitant hypersensitivity to the...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Douglas, C M, Foor, F, Marrinan, J A, Morin, N, Nielsen, J B, Dahl, A M, Mazur, P, Baginsky, W, Li, W, el-Sherbeini, M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45549/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7528927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12907
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