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Quantitative Characterization of the Amount and Length of (1,3)-β-D-glucan for Functional and Mechanistic Analysis of Fungal (1,3)-β-D-glucan Synthase

(1,3)-β-d-Glucan synthase (GS) is an essential enzyme for fungal cell wall biosynthesis that catalyzes the synthesis of (1,3)-β-d-glucan, a major and vital component of the cell wall. GS is a proven target of antifungal antibiotics including FDA-approved echinocandin derivatives; however, the functi...

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Autori principali: Abhishek Chhetri, Anna Loksztejn, Kenichi Yokoyama
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bio-protocol LLC 2021-04-01
Serie:Bio-Protocol
Accesso online:https://bio-protocol.org/en/bpdetail?id=3995&type=0
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