Ibrexafungerp: A First-in-Class Oral Triterpenoid Glucan Synthase Inhibitor
Ibrexafungerp (formerly SCY-078 or MK-3118) is a first-in-class triterpenoid antifungal or “fungerp” that inhibits biosynthesis of β-(1,3)-D-glucan in the fungal cell wall, a mechanism of action similar to that of echinocandins. Distinguishing characteristics of ibrexafungerp include oral bioavailab...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2021-02-01
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| Schriftenreihe: | Journal of Fungi |
| Schlagworte: | |
| Online-Zugang: | https://www.mdpi.com/2309-608X/7/3/163 |
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