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Myeloperoxidase Formation of PAF Receptor Ligands Induces PAF Receptor-dependent Kidney Injury During Ethanol Consumption

Cytochrome P450 2E1 (CYP2E1) induction and oxidative metabolism of ethanol in hepatocytes inflames and damages liver. Chronic ethanol ingestion also induces kidney dysfunction, which associates with mortality of alcoholic hepatitis. Whether kidney is directly affected by ethanol or is secondary to l...

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Publicado en:Free Radic Biol Med
Autores principales: Latchoumycandane, Calivarathan, Nagy, Laura E., McIntyre, Thomas M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554800/
https://ncbi.nlm.nih.gov/pubmed/26003521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.05.020
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