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Myeloperoxidase Formation of PAF Receptor Ligands Induces PAF Receptor-dependent Kidney Injury During Ethanol Consumption

Cytochrome P450 2E1 (CYP2E1) induction and oxidative metabolism of ethanol in hepatocytes inflames and damages liver. Chronic ethanol ingestion also induces kidney dysfunction, which associates with mortality of alcoholic hepatitis. Whether kidney is directly affected by ethanol or is secondary to l...

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Détails bibliographiques
Publié dans:Free Radic Biol Med
Auteurs principaux: Latchoumycandane, Calivarathan, Nagy, Laura E., McIntyre, Thomas M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554800/
https://ncbi.nlm.nih.gov/pubmed/26003521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.05.020
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