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Clinical significance of the integrin α6β4 in human malignancies
Integrin α6β4 is a cellular adhesion molecule that binds to laminins in the extracellular matrix and nucleates the formation of hemidesmosomes. During carcinoma progression, integrin α6β4 is released from hemidesmosomes, where it can then signal to facilitate multiple aspects of tumor progression in...
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| Publié dans: | Lab Invest |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4554527/ https://ncbi.nlm.nih.gov/pubmed/26121317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.82 |
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