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Clinical significance of the integrin α6β4 in human malignancies

Integrin α6β4 is a cellular adhesion molecule that binds to laminins in the extracellular matrix and nucleates the formation of hemidesmosomes. During carcinoma progression, integrin α6β4 is released from hemidesmosomes, where it can then signal to facilitate multiple aspects of tumor progression in...

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Foilsithe in:Lab Invest
Main Authors: Stewart, Rachel L., O’Connor, Kathleen L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554527/
https://ncbi.nlm.nih.gov/pubmed/26121317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.82
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