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Rhoa Function in Lamellae Formation and Migration Is Regulated by the α6β4 Integrin and Camp Metabolism

Clone A colon carcinoma cells develop fan-shaped lamellae and exhibit random migration when plated on laminin, processes that depend on the ligation of the α6β4 integrin. Here, we report that expression of a dominant negative RhoA (N19RhoA) in clone A cells inhibited α6β4-dependent membrane ruffling...

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Détails bibliographiques
Auteurs principaux: O'Connor, Kathleen L., Nguyen, Bao-Kim, Mercurio, Arthur M.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174290/
https://ncbi.nlm.nih.gov/pubmed/10648558
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