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Xanthohumol-mediated suppression of Notch1 signaling is associated with antitumor activity in human pancreatic cancer cells

Pancreatic cancer remains a lethal disease with limited treatment options. At the time of diagnosis, approximately 80% of these patients present with unresectable tumors caused by either locally advanced lesions or progressive metastatic growth. Therefore, development of novel treatment strategies a...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Kunnimalaiyaan, Selvi, Trevino, Jose, Tsai, Susan, Gamblin, T. Clark, Kunnimalaiyaan, Muthusamy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554525/
https://ncbi.nlm.nih.gov/pubmed/25887885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0915
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