Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer

BACKGROUND: The NIMA-related kinase 2 (NEK2) is a serine/threonine kinase that is involved in regulation of centrosome duplication and spindle assembly during mitosis. Dysregulation of these processes causes chromosome instability and aneuploidy, which are hallmark changes of many solid tumors. Howe...

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Pubblicato in:BMC Urol
Autori principali: Zeng, Yan-Ru, Han, Zhao-Dong, Wang, Cong, Cai, Chao, Huang, Ya-Qiang, Luo, Hong-Wei, Liu, Ze-Zhen, Zhuo, Yang-Jia, Dai, Qi-Shan, Zhao, Hai-Bo, Liang, Yu-Xiang, Zhong, Wei-De
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553013/
https://ncbi.nlm.nih.gov/pubmed/26320076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-015-0085-7
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