Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer

BACKGROUND: The NIMA-related kinase 2 (NEK2) is a serine/threonine kinase that is involved in regulation of centrosome duplication and spindle assembly during mitosis. Dysregulation of these processes causes chromosome instability and aneuploidy, which are hallmark changes of many solid tumors. Howe...

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Publicado en:BMC Urol
Autores principales: Zeng, Yan-Ru, Han, Zhao-Dong, Wang, Cong, Cai, Chao, Huang, Ya-Qiang, Luo, Hong-Wei, Liu, Ze-Zhen, Zhuo, Yang-Jia, Dai, Qi-Shan, Zhao, Hai-Bo, Liang, Yu-Xiang, Zhong, Wei-De
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553013/
https://ncbi.nlm.nih.gov/pubmed/26320076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-015-0085-7
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