Overexpression of NIMA-related kinase 2 is associated with progression and poor prognosis of prostate cancer

BACKGROUND: The NIMA-related kinase 2 (NEK2) is a serine/threonine kinase that is involved in regulation of centrosome duplication and spindle assembly during mitosis. Dysregulation of these processes causes chromosome instability and aneuploidy, which are hallmark changes of many solid tumors. Howe...

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Bibliografiska uppgifter
I publikationen:BMC Urol
Huvudupphovsmän: Zeng, Yan-Ru, Han, Zhao-Dong, Wang, Cong, Cai, Chao, Huang, Ya-Qiang, Luo, Hong-Wei, Liu, Ze-Zhen, Zhuo, Yang-Jia, Dai, Qi-Shan, Zhao, Hai-Bo, Liang, Yu-Xiang, Zhong, Wei-De
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553013/
https://ncbi.nlm.nih.gov/pubmed/26320076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-015-0085-7
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