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Modulation of Innate Immune Signalling by Lipid-Mediated MAVS Transmembrane Domain Oligomerization

RIG-I-like receptors detect viral RNA in infected cells and promote oligomerization of the outer mitochondrial membrane protein MAVS to induce innate immunity to viral infection through type I interferon production. Mitochondrial reactive oxygen species (mROS) have been shown to enhance anti-viral M...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Nobre, Luis, Wise, Daniel, Ron, David, Volmer, Romain
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552940/
https://ncbi.nlm.nih.gov/pubmed/26317833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136883
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