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Haplotype-based approach to known MS-associated regions increases the amount of explained risk
Genome-wide association studies (GWAS), using single nucleotide polymorphisms (SNPs), have yielded 110 non-human leucocyte antigen genomic regions that are associated with multiple sclerosis (MS). Despite this large number of associations, however, only 28% of MS-heritability can currently be explai...
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Publicado no: | J Med Genet |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMJ Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4552900/ https://ncbi.nlm.nih.gov/pubmed/26185143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103071 |
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